Neoadjuvant and adjuvant ARPIs in high-risk localized #ProstateCancer. Robert Reiter, MD, UCLA Health joins Zach Klaassen, MD, MSc Georgia Cancer Center to discuss why surgery alone isn’t enough (recurrence up to 70%). Phase II data show better pathologic responses with ADT ARPIs, and phase III trials like PROTEUS and genomic-guided GUNS are underway, plus early signals from neoadjuvant Lu-177 PSMA (LuTectomy). Surgery systemic therapy may become a new paradigm. #WatchNow > bit.ly/4pAMUbk | UroT
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