A study reveals how two proteins cooperate in a key early step of antiviral detection, as reported by researchers at Science ...

Researchers show how LGP2 binds viral RNA ends, moves along the strand, and helps MDA5 form filaments that amplify antiviral signaling. The findings clarify an early defense step and may inform ...

Human norovirus, a positive-strand RNA virus that is the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year, has no ...

Chronic hepatitis B is a viral disease that affects the liver and greatly increases the risks of liver cirrhosis and ...

If your holiday season activities include a luxury cruise or feasting on raw oysters, then beware: Norovirus, a gastrointestinal RNA virus that can cause nausea and diarrhea, could be an unwelcome ...

There is currently no cure for HIV, but medications can help people with the disease manage their symptoms. HIV can still develop into AIDS years after infection, however, even with disease management ...

Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University ...

The innate immune system is the body's first line of defence against pathogens like bacteria or viruses. TRIM25 is a protein that is important in the innate immune response against RNA viruses, such ...

An international team led by researchers at the University of Toronto has found a new RNA virus that they believe is hitching a ride with a common human parasite. We discovered A. odysseus in human ...

For decades, biology textbooks have drawn a firm line: viruses are not alive. They lack the machinery to reproduce on their own, they carry no metabolism, and they depend entirely on host cells to ...